What's New!
New Products
- SMM series Stereotaxic Micromanipulator
- TAKANOME™ (MTK-1) Four-axis Hanging Joystick Oil Hydraulic Micromanipulator
- SR-9M-HT Stereotaxic Instrument (for chronic experiments on mice)
- IM-11-2 Pneumatic Microinjector
Prototype
- Caution:
- Federal law restricts this device to sale by or on the order of a physician or practitioner licensed by the law of the State in which he practices to use or order the use of the device.
New Products
SMM series Stereotaxic Micromanipulator
Robust stereotaxic micromanipulator with precise three-axis movement.
The SMM-100 is a three-axis stereotaxic micromanipulator.
The Y-axis comes standard for the Bregma-Lamda reference on Mice/Rats experiment. In addition, angle adjustment provides flexibility of the movement which is useful in avoiding the blood vessels and so on. The setting can be switched to either AP or ML direction.
The SMM-100 has robust design which promises a smooth and steady control whether tilted and/or holding the heavy apparatus.
The Y-axis knob for AP direction on the brain atlas come standard with SMM-100.
The SMM-100 is equipped with Y-axis for the fine adjustment between Bregma and Lamda and precise movement for the small size brains such as Mice and Rats while the SM-15R/L Stereotaxic micromanipulator, Y-axis unit, SM-15M Substage, is optional.
Full rotation of the knob is 1mm, and minimum graduation is 0.01mm for all axes for the precise control.
The direction of angle can be switched according to the applications.
The angle of SMM-100 can be changed to AP direction (default setting) or ML direction which allows the SMM-100 to be used for a variety of purposes.
Set-up examples of the SMM-100.
SMM-100 is suitable not only for injection, but also for a variety of applications including the electrophysiological recording. Its stable design enables to hold an apparatus such as IMS-20 Stereotaxic Micromanipulator while it is tilted. It also can be used for the study of whisker or somatosensory cortex (barrel).
SMM Series
SMM-200/SMM-200B tilts in two directions, AP and ML simultaneously enabling approach of the target in the desired angle.
SMM-100B/SM-200B is the model without Y-axis which is ideal when Y-axis is not needed, or multiple manipulators are placed in close proximity since there will be no interference of the Y-axes.
| Models | SMM-100 | SMM-200 |
|---|---|---|
| Figures |  |
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| Angle(s) | One direction (AP or ML) Switchable |
<Simultaneous> Two directions (AP & ML) |
* SMM-100B and SMM-200B is featured without the installation of Y-axis unit. Those models (made-to-order) are recommendable when the Y-axis unit is NOT necessary. Especially, electrodes for multi-recording experiment need to be close each other.
Optional products
* To use the SD-101 with the SMM Series, the SM-15C attachment is required. Please feel free to contact us for more information.
MTK-1 Four-axis Hanging Joystick Oil Hydraulic Micromanipulator
The optimal manipulator specifically made for handling suspension cells!
Once having been set, the innovative fan-shaped driver never fails to return to where the pipette tip should be. The newly installed knob allows a pipette to move along its axis by using a traditional and smooth oil hydraulic joystick. This manipulator will spare the laborious work of pipette alignment with the optical axis, providing more time for objective operation.
* A microscope and injectors (IM-11-2) are not included.
* This product is sold as a set of both right and left handed manipulators with a dedicated adaptor.
Easy attachment of a pipette
The injection holder is provided with an anchor (special clasp). This special clamp memorizes the length of the pipette from the injection holder, thus exchanging and repositioning of the pipette is much faster and accurate.
* Design tolerance for attachment of a pipette is 10mm. Pipette location can be corrected within the tolerance so that it can be attached in the usual manner.
Pipette angle adjustment is centered at the tip to stay in view
The pipette tip is designed for staying at the optical axis against any angles. Therefore angle adjustment makes it hard to miss the tip in the field of view.
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| 15° | 40° |
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Simple and reliable motion from Home to Working position
50mm retracting margin enables easy exchange of a pipette. Breakage of pipette is greatly reduced during the replacement.
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| Home position | Working position |
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Mounting on a microscope
| Olympus | Nikon |
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| Carl Zeiss | Leica |
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A dedicated adaptor for each microscope has been developed. It needs no adjustment for mounting so that it can be installed at the best position without fail. Find an appropriate adaptor in the following table.
Microscope compatibility table
| Supplier | Microscope | Model |
|---|---|---|
| Olympus | IX70 | MTK-1-O1 |
| IX71 | MTK-1-O2 | |
| IX73, IX83 | MTK-1-O3 | |
| Nikon | ECLIPSE TE2000 | MTK-1-N1 |
| ECLIPSE Ti | MTK-1-N2 | |
| Carl Zeiss | Axiovert 200, Axio Observer 3/5/7 | MTK-1-Z1 |
| Axio Vert.A1 | MTK-1-Z2 | |
| Leica | DMi8 | MTK-1-L2 |
* Depending on the specifications of the stage, plate insert or thermos-plate, a special-made adaptor may be required. Please contact us for more information.
* This product is sold as a set of both right and left handed manipulators and a dedicated adaptor. It cannot be sold separately.
For product details and price information, please feel free to contact us.
Information Center
SR-9M-HT Stereotaxic Instruments (for Chronic Experiments on Mice)
* Stereotaxic micromanipulators such as SM-15R is sold separately.
NEW Concept for mouse chronic experiments:
We have developed a NEW concept for stereotaxic instrument for mice. It can be used for chronic experiments and/or under the microscope.
"Chamber Frame for SR-9M-HT" is a disposable item. Five pieces of chamber frames are included as an accessory to the SR-9M-HT. A 10-piece pack of chamber frames is sold separately as Model "CF-10".
How to use:
The most striking feature of the SR-9M-HT is the "chamber frame", which can be bonded to the head of a mouse after conventional three-point fixation (mouth, nose and ears). After bonding onto the head of a mouse, the "chamber frame" is all that is needed to fix the mouse in place.
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| 1. Three-point fixation | 2. Fix head to a chamber | 3. Chamber fixation done! |
The flexible design finds wide applicability:
- Chronic experiment:
- Fixed on SR-9M-HT ⇔ Free It enables repeated experiments.
- Visual and Olfactory experiment:
- With the mouth/nose piece removed, it provides open space in front, enabling visual and olfactory experiments.
- Behavioural experiment:
- With only a chamber frame fixed on the head (thus free to move), it permits observation of its behaviour.
- Auditory experiment:
- With ear bars and auxiliary ear bars removed, it permits auditory experiments.
- Observation by optical microscope:
- It permits observation under a microscope.
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| Auditory and Visual experiments | Observation by microscope |
SR-9M-HT Products line:
 Full set |
Model No. : SR-9M-HT
* Stereotaxic micromanipulators such as SM-15R is sold separately. |
 Upper plate only |
Model No. : SR-9AM
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 Simple head holding |
Model No. : MAG-1
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Chamber Frame (1 set / 10 pcs.) |
Model No. : CF-10
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For product details and pricing information, please feel free to contact us directly.
Information Center
IM-11-2 Pneumatic Microinjector
Give it a try and experience the smooth response.
Narishige's Pneumatic Microinjector
| Ready-to-use Air microinjector. No oil required. |
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 No More! Filling Oil |
 No More! Air Bubbles |
 No More! Syringe Leakage |
| New Injection Holder. Easy to control air pressure. |
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No Oil Refill Required. Everything Pneumatic!
Superior performance of an oil hydraulic injector can be fully achieved by this new pneumatic control system.
Narishige has unveiled a new injector that is easy to use, even for a beginner.
- A Change from Hydraulic Control to Pneumatic
- For example, catching and releasing of a micro-object in liquid by charge and discharge of air pressure can be controlled more easily, as compared to using an oil-hydraulic-injector.
- Oil and Maintenance Free
- There is no need to fill oil into this injector. Install the capillary, and it is ready to use. The air pressure can be controlled with the same response as using an oil hydraulic injector.
- Smooth Pneumatic Control
- This pneumatic injector was designed to have smooth control. It is designed to be the same quality that Narishige is known for. The smooth pneumatic control will surprise you.
Three Simple Steps!
Usually, many steps are required to set a capillary on the microscope, however the new IM-11-2 injector requires only three steps.
STEP 1Install your capillary * Unlike an oil hydraulic injector, there is no need to adjust the oil level or check for air bubbles. |
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STEP 2Bring the capillary into the field of view of the microscope. |
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STEP 3Move the capillary lower until it dips into the liquid (PVP, etc.) used for the experiment. |
* Allow the capillary to soak up an adequate amount of liquid. |
All set!After soaking up the liquid, now it is ready to control! |
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Features
FEATURE ➊
Easy tubing connection
The fitting mechanism permits one-touch simple insertion and removal of the tubing, thereby making regular care so much easier such as cleaning inside of injection holder.
Incorporates a 360 degree rotating flexible swivel mechanism that prevents a kink in the tubing from being transmitted to the injection holder, thereby enabling delicate adjustment of the rotating direction of the needle tip.
| Easy tubing release | 360° rotating mechanism |
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FEATURE ➋
Only one-touch for pressure-free
Outfitted with a one-touch pressure relief valve that allows pressure to escape. Compared to the existing screw valve, new pressure relief valve 
makes it easy to adjust interfacial surface in the pipette or the volume of the syringe (FEATURE 3.)
FEATURE ➌
Adjust the pneumatic responsiveness at your own
Pressure changeability in the pipette tip can be adjusted by changing the volume of the syringe, thereby adjusting operational responsiveness according to your preference.
This is a great advantage of using pneumatic injector. The user may simply use the improved pressure relief valve, and adjust the responsiveness, even when the pipette holds a sample inside.
FEATURE ➍
Wide movement range & pressure changeability
Through the adoption of a long syringe and a coarse-fine coaxial control knob, the amount of pressure change per knob rotation has increased by approx. 25 times,* which helps achieve a wide range of pressure changeability.
* The data was surveyed by in-house testings. The IM-11-2 was set as the standard ICSI usage. The coarse pressure values were measured at the range between the front 5mm and the rear 5mm.
Controlling the volume of syringe to your own preference by illustration
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For product details and pricing information, please feel free to contact us or our authorized dealers.
- Caution:
- Federal law restricts this device to sale by or on the order of a physician or practitioner licensed by the law of the State in which he practices to use or order the use of the device.
Please give us your thoughts about the new IM-11-2 >> Questionnaire
Prototype
These New Products Have Made Their Debut at the 38th Annual Meeting of the Society for Neuroscience in Washington, D.C.
Your Needs Evolve Into Our Products.
Stereotaxic Gets Easier to Use.
Stereotaxic Adaptor Prototype
| Ever-Evolving Narishige Stereotaxic Instruments | |
|---|---|
 SR-5N |
SR-5/6 Improved. Released in 1991. |
 SR-5R-HT |
Compared to SR-5N, the auxiliary ear bar and the mouth/nose fixing metal adopted the devetail structure, which achieves an excellence of smooth position adjustment. The current model with a good reputation since its released in 2004. |
Prototype
With this prototype, we made a further improvement to SR-5R-HT, the nose fixing metal have become much easier to use.
| Improvements on Nose Fixing Metal | |
|---|---|
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As usual, when the knob is rotated, the nose fixing metal adjusts the angle in the vertical direction, which makes it possible to fix the animal's upper jaw. |
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Different from the previous one, this prototype has a small knob on the side. Loosening the knob to pull out the whole part of the nose fixing metal in an upward direction provides sufficient space that makes it easier to hook the animal's teeth. |
  Type C / Type T |
The nose fixing metal is offerd in two types of shape; old & new. You can choose whichever fits better to the animal, and either one you choose, they are compatible with each other. |
We welcome various requests from customers.